Which peptide will I get?

Your clinician reviews your intake — health history, sleep, training, and goals — and prescribes sermorelin at the protocol that fits, only if treatment is appropriate.

How is this different from taking HGH?

Synthetic HGH delivers external growth hormone directly, bypassing your body's own signaling. Sermorelin is a secretagogue: it prompts your pituitary to release its own growth hormone in natural pulses, with your body's feedback loops still in charge. Pillar does not prescribe synthetic HGH.

Are compounded peptides FDA-approved?

No — compounded medications are not FDA-approved. Sermorelin is prescribed by licensed clinicians and prepared by licensed US compounding pharmacies under state and federal pharmacy regulations. Your clinician only prescribes what's appropriate and legal in your state.

What are the side effects?

The most commonly reported side effects are injection-site reactions such as redness or irritation, along with headache or flushing, and they're usually mild. Peptide therapy isn't appropriate for everyone — including during active malignancy — so tell your clinician about your full health history and every medication you take during intake.

Will I stay on peptides forever?

No — protocols are cycled by design. Sermorelin runs in 12-week cycles. At each reassessment, you and your clinician decide whether to continue, pause, or stop based on how you responded. Stop points are built in from the start.

Is treatment available in my state?

Pillar is available in 48 states and Washington, D.C. — we are not currently available in Mississippi or Alaska. Availability is confirmed during intake. Prescribing rules for compounded peptides vary by state, and your clinician will let you know if any limitations apply where you live. If therapy is appropriate, transaction and fulfillment are handled by the approved external treatment platform or dispensing pharmacy.

Peptide therapy

Growth hormone declines with age. Support your body's own production.

Sermorelin signals your body to release its own growth hormone — prescribed by a US-licensed clinician, only if appropriate.

Private online evaluation by a US-licensed clinician
Compounded by licensed US compounding pharmacies
Clinician-monitored dosing with built-in stop points

Start your visit

US-licensed clinicians

Licensed US compounding pharmacies

Ongoing clinical monitoring

Prescription medications require an evaluation by a licensed clinician. Individual results vary.

The Pillar standard for peptide therapy

US-licensed clinicians

Every protocol is prescribed and supervised by a licensed clinician — never sold direct.

US compounding pharmacies

Peptides are compounded by licensed US pharmacies, with fulfillment handled by the approved external treatment platform or dispensing pharmacy.

Monitoring built in

Check-ins, dose adjustments, and stop points are part of every protocol.

Private end to end

Private online intake and secure messaging through the approved external platform.

Somatopause

You aren't imagining it — growth hormone output falls with age

Growth hormone secretion peaks in your twenties and declines steadily after — a shift researchers call somatopause.

Somatopause

Age-related decline

Natural growth hormone output tends to decline with age — the pattern peptide therapy aims to support.

Educational overview — not a diagnosis. A licensed clinician evaluates whether peptide therapy is appropriate for you.

GH and deep sleep

Most growth hormone is released in pulses during the deeper stages of sleep.

Pulsatile signaling

GHRH directs those pulses — sermorelin is an analog of that signaling hormone.

A gradual decline

Whether the decline warrants treatment is an individual question — evaluated with a licensed clinician.

Why secretagogues — not synthetic HGH

GHRH analogs signal your pituitary to release its own growth hormone in natural pulses — not replace it from outside.

Works with your body's own signaling

GHRH peptides (what Pillar prescribes)

Pulsatile — your body's own rhythm

Signals your pituitary to release its own growth hormone in physiologic pulses
Your body's natural feedback loops stay in charge of how much is released
Prescribed by a US-licensed clinician and compounded by licensed US pharmacies
Cycled protocols with clinician oversight and built-in stop points

Replaces the hormone from outside

Synthetic HGH injections

Constant, non-pulsatile level

Delivers external growth hormone directly, bypassing your body's own signaling
Overrides natural feedback loops — levels depend entirely on the dose
FDA-approved only for specific diagnosed deficiencies and conditions
Not something Pillar prescribes

Compounded sermorelin is a prescription medication prepared by licensed US compounding pharmacies. Compounded medications are not FDA-approved. A clinician determines whether therapy is appropriate for you.

What your protocol includes

Clinician oversight from intake through reassessment. Fulfillment is handled by the approved external treatment platform or dispensing pharmacy.

Compounded peptide supply

Your prescribed peptide, compounded by a licensed US pharmacy and shipped with clear dosing instructions.

Clinician oversight

A midpoint check-in on 12-week sermorelin cycles, with dose adjustments when clinically appropriate.

Message your care team

Message your clinical team anytime through the secure portal.

Cycling and stop points

Cycled, reassessed, and stopped if therapy is no longer appropriate.

Exact protocol contents depend on the medication your clinician prescribes. Pricing for each protocol is shown below.

Man enjoying an active lifestyle outdoors

How to get started

100% online, from intake through clinician review.

Complete a private intake

About 5 minutes on your health history, training, sleep, and goals.

A clinician reviews

A US-licensed clinician reviews, usually within 24 hours.

Prescription, if appropriate

If appropriate, your clinician prescribes sermorelin.

Ongoing oversight

A licensed US pharmacy ships your prescription; your clinician monitors throughout.

Get startedMedications and treatments are subject to a valid prescription issued by a licensed healthcare provider.

What to expect, phase by phase

Every protocol follows a structured cadence of dosing, check-ins, and reassessment. Here's how a typical 12-week cycle is managed.

Weeks 1–4

Getting started

Begin your prescribed protocol — your care team is a message away.

Weeks 5–8

Midpoint check-in

Your clinician reviews how it's going and adjusts if clinically appropriate.

Weeks 9–12

Completing the cycle

Finish the cycle as prescribed ahead of reassessment.

After 12 weeks

Reassess together

Continue, pause, or stop — decided together. Stop points are built in.

Individual results vary and no specific outcome is guaranteed. Your clinician monitors your response throughout the protocol.

A care team that actually follows up

Your clinician designs the protocol, monitors your response, and adjusts it — with your care team a message away.

Your own clinician

The same US-licensed clinician, from first review to final reassessment.

Unlimited messaging

Message your care team anytime — no appointment needed.

Reviewed at every step

Dosing reviewed at every check-in; stopped if no longer appropriate.

One protocol. One decision — made with a clinician.

A GHRH analog that prompts your body's own growth hormone release — prescribed in structured, clinician-supervised cycles.

You don't have to pick — your clinician prescribes the protocol that fits, only if appropriate.

Bestseller

Sermorelin

GHRH analog · 12-week cycles

Works with your body's own GH signaling

A GHRH analog that signals your pituitary in physiologic pulses — prescribed in 12-week cycles when appropriate.

GHRH-analog signaling — your body's feedback loops stay in charge
Prescribed as a full 12-week clinical cycle
Clinician check-in at the cycle midpoint

Price locked in for life

$199.00/month

View Details

Product images are for illustration only. Packaging may vary.

Why Pillar

How we compare

Published sermorelin protocols at one leading US clinic run $299–$399 a month, and advertised intro prices elsewhere can rise at renewal. Pillar is one flat monthly price with your care included.

What the advertised price covers

Pillar

Care + medicationEvaluation, your 12-week protocol if prescribed, and a midpoint clinician check-in

Competitor

Often medication + extrasMemberships, consults, or labs can bill separately

Sermorelin — monthly price

Pillar

$199/monthOne monthly price — no membership on top

Competitor

$299–$399/monthOne leading clinic's published protocol; independent 2026 research puts typical steady-state pricing at $120–$200/month, with some plans higher

Required membership on top

Pillar

$0No membership fees, ever

Competitor

At some clinicsLab-first platforms bill a membership plus medication

Price locked in for life

Pillar

Competitor

Not publishedAdvertised intro rates can step up at renewal

Midpoint clinician check-in included

Pillar

Competitor

Varies

Comparison of Pillar Health and US peptide telehealth clinics across sermorelin pricing, memberships, and program terms.
Compare	Pillar HealthCare + medication included	CompetitorUS peptide telehealth clinics
What the advertised price covers	Care + medicationEvaluation, your 12-week protocol if prescribed, and a midpoint clinician check-in	Often medication + extrasMemberships, consults, or labs can bill separately
Sermorelin — monthly price	$199/monthOne monthly price — no membership on top	$299–$399/monthOne leading clinic's published protocol; independent 2026 research puts typical steady-state pricing at $120–$200/month, with some plans higher
Required membership on top	$0No membership fees, ever	At some clinicsLab-first platforms bill a membership plus medication
Price locked in for life	Yes	Not publishedAdvertised intro rates can step up at renewal
Midpoint clinician check-in included	Yes	Varies

Competitor figures reflect published US sermorelin pricing as of September 2026 — one leading clinic's posted protocol range and independent pricing research. Plans and prices vary and may change. Pillar price shown is our current program price.

What people say

On clinician-supervised peptide protocols.

"The intake was quick and my clinician actually explained the reasoning — why sermorelin over anything else, what the cycle looks like, and when we'd reassess."

Marcus T.

Sermorelin protocol

"Having a real clinician a message away made the difference. Every question I had about dosing got answered within a day."

James K.

Sermorelin protocol

Individual experiences vary. Results are not guaranteed.

Frequently Asked Questions

Evidence and education

Learn before a treatment decision

Read source-backed guides about prescription review, medication information, and preparing for a visit.

View library

Medication basics6 min read

FDA-Approved and Compounded Medications: What Is Different?

FDA-approved drugs and compounded preparations do not pass through the same premarket review. Knowing that regulatory difference makes product descriptions easier to evaluate.

Read guide

Care process5 min read

Why Medication Review Starts With Your Full Health History

A medication decision depends on more than the symptom that brought you to care. Current medicines, supplements, allergies, and health conditions can change what needs to be discussed.

Read guide

Medication basics5 min read

How to Check an Online Pharmacy Before Filling a Prescription

A professional-looking website is not proof that an online pharmacy is licensed or legitimate. Independent verification is a separate step.

Read guide

Work with your biology, not against it

Start your private online visit today. A US-licensed clinician reviews your intake and designs a protocol — only if it's right for you.

Start your visit

Sermorelin is prescribed in 12-week clinical cycles

US-licensed clinicians

Licensed US compounding pharmacies

Built-in stop points

Transaction and fulfillment via the approved external treatment platform

Medications and treatments are subject to a valid prescription issued by a licensed healthcare provider. Sermorelin is a prescription medication; a clinician will determine whether peptide therapy is appropriate based on your intake.

Compounded medications are prepared by licensed US compounding pharmacies and are not FDA-approved. Prescribing is at the discretion of a licensed clinician where permitted by state law.

Peptide therapy is not appropriate during active malignancy. Tell your clinician about your full health history and all medications during intake.

Content on this page is educational and does not guarantee any specific result. Individual results vary.

Product images are for illustration only. Packaging may vary.