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Your treatment at a glance
Bi-Est Cream
Two estrogens, one cream. Your clinician picks the mix.
Availability
Bi-Est Cream
$129.00/month
Billed monthly.
Bundled treatment plan: clinician review, your medication if prescribed, and ongoing care. No fees beyond the monthly price. Plan terms
Bi-Est Cream is coming soon. You will start it here with a secure treatment questionnaire — visit this page again soon or view the product details below.
Program Highlights
- Review by a US-licensed clinician
- Mix and dose set by your clinician
- Messaging with your clinical team
What's included
Every treatment on Pillar comes with the same clinician-led care — no matter which program you start.
Everything you need,
nothing you don't.

What is Bi-Est Cream?
Hot flashes and night sweats getting in the way? Bi-Est Cream blends two estrogens, estriol and estradiol, in one cream you rub into your skin. It comes in two mixes, 50/50 or 80/20, and your clinician picks the mix and the dose for you. Start with a secure questionnaire. A US-licensed clinician reviews it and prescribes only if hormone therapy is right for you.
Included in your program
- Review by a US-licensed clinician
- Mix and dose set by your clinician
- Messaging with your clinical team
Who's eligible?
- Women 18+ in eligible US states
- For women in perimenopause or menopause
- Not for women with a history of breast cancer, blood clots or stroke
Important safety information
Common side effects, who Bi-Est Cream is not for, and what to tell your clinician. A summary of key warnings, not complete prescribing information.
Explore related programs
Common questions,
answered.
Open any question to read the complete answer.
Details
Compounded Bi-Est (estriol and estradiol) body cream for menopause, prescribed online through a secure questionnaire.
Bi-Est Cream: Billed monthly.
- Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Prescription required.
- Every monthly plan renews each month until you cancel. To cancel, click Cancel in your account. No refunds once your medication ships. Plan terms
- The dispensing pharmacy provides medication fulfillment details.
- Product images are for illustration only. Packaging may vary.



